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Ryoji Noyori Prize Recipients

 
     
 

YEAR 2014 2013  2012  2011 2010  2009  2008  2007  2006  2005  2004  2003  2002

 

Barry M. Trost
The Winner of the Prize for the award year 2014
Professor Dieter Enders
Seniorprofessor RWTH Aachen University, Germany
Professor Enders is a pioneer in the field of asymmetric synthesis. He has developed first broadly applicable chiral auxiliaries, such as SAMP/RAMP and demonstrated their efficiency in numerous natural product syntheses. He also established the field of asymmetric carbon - carbon bond formations catalyzed by N-heterocyclic carbenes and made seminal other contributions to the field of organocatalysis.

Professor
Barry M. Trost

Job and Gertrud Tamaki Professor of Humanities and Sciences, Stanford University, U.S.A.

Professor Trost characterized by a very high order of imagination, innovation and scholarship, has repeatedly led to the invention of new synthetic reactions and demonstrated their effectiveness by the design of new strategic approaches for the total synthesis of bioactive molecules and has made important contributions in evolving some of the concepts of green chemistry, notably atom economy.

Professor
Masakatsu Shibasaki

Professor, Director of Institute of Microbial Chemistry (BIKAKEN) and Emeritus Professor: The University of Tokyo, Hokkaido University, Japan.

Professor Shibasakihas established the concept of cooperative asymmetric catalysis, developing many reactions with high atom economy. His accomplishments are also successfully highlighted in his catalytic asymmetric syntheses of bioactive compounds.


Professor
Hisashi Yamamoto

Professor, Department of Chemistry, The University of Chicago, U. S. A.

Professor Yamamotowas pioneered the use of binaphthol as a key ligand for chiral Lewis acid catalysts, which was the forerunner of a C-2 symmetry based chiral acid catalyst. His combined Bronsted and Lewis acid catalysts are the most efficient among the asymmetric acid catalyst and his super Bronsed acid catalysts play an important role in the step-economical synthesis of complex molecules. He also introduced V, Zr, Hf, and Fe catalysts for asymmetric oxidation. These achievements have had a seminal impact in asymmetric synthesis.


Professor
Eric N. Jacobsen

Professor, Department of Chemistry & Chemical Biology, Harvard University, U. S.A.

Professor jacobsen discovered useful, chiral salen-based catalysts for asymmetric epoxidation of simple olefins, as well as effective new catalysts for aziridnation, Diels-Alder, conjugate addition, hydrocyanation, and epoxide ring-opening reactions. He also pioneered the use of hydrogen-bonding catalysts in asymmetric synthesis. These methodologies, together with the mechanistic insights he has uncovered about them, have had a profound impact both in academia and in industry.


Professor
Yoshio Okamoto

Distinguished Invited University Professor, Nagoya University & Chair Professor, Harbin Engineering University

Professor Okamoto has made significant contribution to the areas of synthesis of helical polymers and their application to chiral separation of enantiomers. He was the first to succeed in the synthesis of one-handed helical polymer by asymmetric polymerization, and found its high chiral recognition ability to many racemic compounds. Using the polymer, he successfully developed a practical chiral packing material for HPLC. His another outstanding contribution is the development of very useful chiral packing materials based on helical polysaccharide derivatives, which are widely used throughout the world.

Professor
Andreas Pfaltz

Department of Chemistry, University of Basel, Switzerland.

Professor Pfaltz is well known for his seminal contributions to asymmetric catalysis. The semicorrins developed in his group served as the prototype for an important new family of nitrogen ligands, the bisoxazolines, which have found widespread use in catalytic asymmetric synthesis. His work on phosphinooxazolines, known as PHOX ligands, has led to numerous efficient chiral transition metal catalysts. Most noteworthy are iridium-PHOX and related complexes, which are the first catalysts that allow highly enantioselective hydrogenation of unfunctionalized, purely alkyl-substituted olefins and, therefore, greatly enhance the scope of asymmetric hydrogenation.

Professor
Tamio Hayashi

Department of Chemistry, Graduate School of Science, Kyoto University, Japan

Professor Hayashi is best known for his insightful and seminal contributions to the area of catalytic asymmetric synthesis, especially carbon-carbon bond forming reactions using chiral transition metal catalysts. He was the first to succeed in palladium-catalyzed asymmetric cross-coupling, gold-catalyzed asymmetric aldol-type reaction, and rhodium-catalyzed asymmetric addition reactions. His another outstanding contribution is the development of new and powerful chiral ligands. Chiral ferrocenylphosphines have been widely used for various types of asymmetric reactions, and the chiral dienes he designed recently are attracting particular attention as an unprecedented type of chiral ligands.

Professor
David A. Evans

Department of Chemistry and Chemical Biology, Harvard University,
Cambridge, USA.

Professor Evans has made significant advances in the design of stereoselective reactions and the applications of these reactions to natural products synthesis. Especially enantioselective Diels-Alder, Michael, and aldol reactions are three of the important families of processes developed in his group. In the area of synthetic design, he has archieved synthesis of complex natural products through the exclusive use of chiral auxiliaries to control stereochemical relationships. Evans' chiral auxiliaries and chiral catalysts for enantioselective bond formation are widely used in both industrial and academic laboratories throughout the world.

Professor
Tsutomu Katsuki

Department of Chemistry, Faculty of Science, Graduate School, Kyushu University, Fukuoka, Japan

Professor Katsuki has been contributing to advancement of ecological asymmetric synthesis as a leading chemist, demonstrating the power of molecular catalysis comparable to that of enzyme. He has discovered asymmetric epoxidation of allylic alcohols in collaboration with Professor K. Barry Sharpless and recently reported asymmetric epoxidation of simple olefins using aqueous hydrogen peroxide. He first introduced chiral catalysts activated by photo-irradiation and realized various aerobic asymmetric oxidations

Professor
Dieter Seebach

Laboratorium fur Organische Chemie, ETH Honggerberg, Switzerland

Professor Seebach has been serving as one of the top scientists more than four decades, creatingsa range of new concepts and paradigms in organic synthesis. His contributions have made ever-increasing impact not only on fundamental as well as practical organic synthesis, but also on various related fields, including material sciences and biochemical fields.

Professor
Gilbert Stork

Department of Chemistry, Columbia University, New York, U.S.A.

Professor Stork has been leading the field of organic synthesis for over half a century. With his cantharidin synthesis and the Stork-Eschenmoser hypothesis of steroid synthesis in the 1950's, he introduced the concept of "stereoselective organic synthesis" and created a number of fundamental synthetic methods such as enamine and enol silyl ether methodologies and radical cyclization. In 2001, he published the first completely stereoselective total synthesis of quinine.

Emeritus Professor
Henri B. Kagan

Laboratoire de Synthese Asymetrique
Universite Paris-Sud France

Professor Kagan has been a leader in the field of asymmetric synthesis, presenting many first examples including those of asymmetric synthesis using circularly polarized light, a chiral bidentate diphosphine ligand (DIOP), and a chiral "homogeneous" supported catalyst.
 
 

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