Professor Yoshito Kishi
Morris Loeb Professor of Chemistry, Emeritus, Harvard University, U.S.A.
Professor Kishi has been engaged in a wide range of research on complex natural products with significant biological activities. He pioneered the area of acyclic stereocontrol, completed the total synthesis of numerous complex natural products including neurotoxins (palytoxin, tetrodotoxin, etc.), polyether antibiotics (monensin, lasalocid A, etc.) and antitumor natural products (halichondrins, mitomycin, etc.), and advanced a new concept for stereochemistry assignment of complex organic molecules. Notably, his research efforts on the halichondrin class of marine natural products paved the way for the successful creation of Eisai’s anticancer drug Halaven (Eribulin mesylate).
Professor David W. MacMillan
Department of Chemistry, Princeton University, U.S.A.
Professor MacMillan has been a pioneer in both the areas of organocatalysis and photoredox catalysis. Within organocatalysis he invented the area of iminium catalysis and made significant contributions to hydrogen-bonding catalysis, including the development of the MacMillan organocatalysts. He has also been a leader in bringing the field of photoredox catalysis to synthetic organic chemistry. This new area already has widespread applications in the pharmaceutical industry.